[1]张芸 魏俊雯 徐若然 喻学婷 王鼎珍 马克龙.中医药治疗炎症相关性结直肠癌研究进展[J].陕西中医药大学学报,2022,(05):171-174.[doi:10.13424/j.cnki.jsctcm.2022.05.035]
　ZHANG Yun WEI JunwenXU RuoranYU Xueting WANG Dingzhen MA Kelong.Research Progress of Chinese Medicine in Treatment of Inflammation Related Colorectal Cancer[J].Journal of Shaanxi University of Traditional Chinese Medicine,2022,(05):171-174.[doi:10.13424/j.cnki.jsctcm.2022.05.035]
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中医药治疗炎症相关性结直肠癌研究进展()
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《陕西中医药大学学报》[ISSN:2096-1340/CN:61-1501/R]

卷:
期数:
2022年05期
页码:
171-174
栏目:
出版日期:
2022-09-20

文章信息/Info

Title:
Research Progress of Chinese Medicine in Treatment of Inflammation Related Colorectal Cancer
文章编号:
2096-1340(2022)05-0171-04
作者:
张芸1 魏俊雯1 徐若然1 喻学婷1 王鼎珍1 马克龙1; 2
1.安徽中医药大学，安徽 合肥 230012；
2.安徽省中医药科学院，安徽 合肥 230012
Author(s):
ZHANG Yun1 WEI Junwen1XU Ruoran1YU Xueting1 WANG Dingzhen1 MA Kelong1; 2
1.College of Integrated Chinese and Western Medicine/College of Life Sciences,Anhui University of Chinese medicine,Hefei 230012,China;
2.Institute of Integrated Chinese and Western Medicine, Anhui College of Chinese medicine,Hefei 230012,China
关键词:
关键词：结直肠癌; 溃疡性结肠炎; 中医药; 研究进展
Keywords:
Key words： Colorectal cancer; Ulcerative colitis; Traditional Chinese medicine; Research progress
分类号:
R256.3
DOI:
10.13424/j.cnki.jsctcm.2022.05.035
文献标志码:
A
摘要:
摘 要：目的 综述中医药治疗炎症相关性结直肠癌的研究与治疗进展。方法 中医药治疗炎症性结直肠癌发挥着重要作用与优势，现通过对近几年的相关文献进行梳理，从病因病机、实验研究、临床实践及预防等方面做一综述。结果 实验研究和具体的临床治疗都肯定了中医药治疗的效果，但尚未被广泛推广，仍有不足。结论 中医药成为治疗炎症性结直肠癌的重要思路与方法，效果明显，同时需不断的发现与发展。
Abstract:
Abstract： Objective To summarize the research and treatment progress of traditional Chinese medicine in the treatment of inflammation related colorectal cancer.Methods Traditional Chinese medicine plays an important role in the treatment of inflammatory colorectal cancer.This paper reviews the relevant literature in recent years from the aspects of etiology,pathogenesis,experimental research,clinical practice and prevention.Results Experimental research and specific clinical treatment have confirmed the effect of traditional Chinese medicine treatment,but it has not been widely promoted,and there are still deficiencies.Conclusion Traditional Chinese medicine has become an important idea and method for the treatment of inflammatory colorectal cancer,and the effect is obvious.At the same time,it needs continuous discovery and development.

参考文献/References:

［1］Bray Freddie，Siegel Rebecca L，Torre Lindsey A，et al.Global cancer statistics 2018：GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries［J］.CA：a cancer journal for clinicians，2018，68(6):394-424.
［2］Yashiro Masakazu.Ulcerative colitis-associated colorectal cancer［J］.World journal of gastroenterology，2014，20(44)：16389-16397.
［3］Yan PG，Wang YN，Yang H，et al.Whole Exome Sequencing of Ulcerative Colitis-associated Colorectal Cancer Based on Novel Somatic Mutations Identified in Chinese Patients［J］.Inflammatory bowel diseases，2019，25(8):1293-1301.
［4］牙韩清，郑琴芳，何志钧.溃疡性结肠炎相关结直肠癌手术治疗现况［J］.医学信息，2020，33(7):44-48.
［5］Wang YN，Li J，Zheng WY，et al.Clinical characteristics of ulcerative colitis-related colorectal cancer in Chinese patients［J］.Journal of digestive diseases，2017，18(12)：684-690.
［6］Ryuk JP，Choi GS，Park JS，et al.Predictive factors and the prognosis of recurrence of colorectal cancer within 2 years after curative resection［J］.Annals of surgical treatment and research，2014，86(3):143-151.
［7］杨洋，惠阳，王战争，等.结直肠癌患者中医证型和细胞免疫功能的相关性分析［J］.陕西中医药大学学报，2019，42(3):102-107.
［8］徐立群，张荣华.中药围方配合化疗治疗结直肠癌的思路与方法探讨［J］.云南中医中药杂志，2018，39(7):21-24.
［9］林小常.芍药汤调控炎症因子改善EMT防治结肠炎相关癌的机制研究［D］.广州：南方医科大学，2015.
［10］徐香琴.根皮素对AOM/DSS诱导的溃疡性结肠炎相关性结肠癌防治作用研究［D］.广州：广州中医药大学，2016.
［11］Deng SJ，Tang Q，Fan H，et al.Uncovering the Anticancer Mechanism of Compound Sophorae Decoction against Ulcerative ColitisRelated Colorectal Cancer in Mice［J］.EvidenceBased Complementary and Alternative Medicine，2019，2019:1-16.
［12］Wang XY，Saud SM，Zhang XW，et al.Protective effect of Shaoyao Decoction against colorectal cancer via the Keap1Nrf2ARE signaling pathway［J］.Journal of Ethnopharmacology，2019，241：111981.
［13］李方，郑楠，赵亚娇，等.复方血竭制剂对小鼠溃疡性结肠炎相关结直肠癌的疗效及可能机制［J］.安徽医科大学学报，2017，52(1)：13-17.
［14］严小军，谢斌，姚亮亮，等.养阴化瘀解毒方治疗结肠炎相关性结肠癌前病变26例［J］.江西中医药，2011，42(12):30-32.
［15］董庆志.愈溃消息方联合美沙拉嗪治疗溃疡性结肠炎相关性息肉的临床和实验研究［D］.北京：北京中医药大学，2014.
［16］Li YH，Sun W，Zhou BJ，et al.iTRAQ-based pharmacoproteomics reveals potential targets of berberine，a promising therapy for ulcerative colitis［J］.European journal of pharmacology，2019，850：167-179.
［17］Tao YL，Zhan SB，Wang YB，et al.Baicalin，the major component of traditional Chinese medicine Scutellaria baicalensis induces colon cancer cell apoptosis through inhibition of oncomiRNAs［J］.Sci Rep，2018，8(1)：14477.
［18］Hata K，Anzai H，Fukushima K，et al.Surveillance Colonoscopy for Ulcerative Colitis-Associated Colorectal Cancer Offers Better Overall Survival in RealWorld Surgically Resected Cases［J］.Am J Gastroenterol，2019，114(3)：483-489.

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备注/Memo

备注/Memo:
基金项目：安徽省高校自然科学基金重点项目（KJ2019A0476）;安徽省高校优秀青年人才项目（gxyq2019030）;大学生创新创业训练计划项目（201910369029，S201910369051）
更新日期/Last Update: 2022-09-23