[1]陈丽霞郭苗苗李儒婷彭剑飞张惠玲王靓施慧.中医药辨治糖尿病心脏病用药规律分析[J].陕西中医药大学学报,2024,(03):074-81.[doi:10.13424/j.cnki.jsctcm.2024.03.011]
 CHEN LixiaGUO MiaomiaoLI RutingPENG JianfeiZHANG HuilingWANG LiangSHI Hui.Analysis on Medication Rule of Diabetes Heart Disease Treated by Traditional Chinese Medicine[J].Journal of Shaanxi University of Traditional Chinese Medicine,2024,(03):074-81.[doi:10.13424/j.cnki.jsctcm.2024.03.011]
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中医药辨治糖尿病心脏病用药规律分析()
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《陕西中医药大学学报》[ISSN:2096-1340/CN:61-1501/R]

卷:
期数:
2024年03期
页码:
074-81
栏目:
出版日期:
2024-05-20

文章信息/Info

Title:
Analysis on Medication Rule of Diabetes Heart Disease Treated by Traditional Chinese Medicine
文章编号:
2096-1340(2024)03-0074-08
作者:
陈丽霞1郭苗苗1李儒婷1彭剑飞1张惠玲1王靓2施慧1
1.安徽中医药大学护理学院,安徽 合肥 230012;
2.安徽中医药大学中西医结合学院,安徽 合肥 230012
Author(s):
CHEN Lixia1GUO Miaomiao1LI Ruting1PENG Jianfei1ZHANG Huiling1WANG Liang2SHI Hui1
1.School of Nursing,Anhui University of Chinese Medicine,Hefei 230012,China;
2.School of Integrated Chinese and Western Medicine,Anhui University of Chinese Medicine,Hefei 230012,China
关键词:
关键词:糖尿病心脏病数据挖掘隐结构频繁项集用药规律
Keywords:
Key words:DiabetesHeart diseaseData miningHidden structureFrequent itemsetsMedication patterns
分类号:
R259
DOI:
10.13424/j.cnki.jsctcm.2024.03.011
文献标志码:
A
摘要:
摘要:目的 基于现代文献探究糖尿病心脏病的用药规律。方法 检索中国知网(CNKI)、中国生物医学文献数据库(CBM)等数据库建库至2021年12月收录的有关中药辨治糖尿病心脏病的文献。分别使用Lantern 5.0、Weka 3.8.5软件,对药物及症状进行隐结构分析以及药物与药物、药物与证型、药物与症状的频繁项集分析。结果 共计文献131篇。数据挖掘分析常用症状51项,包括苔白、面色少华、头晕等;药物使用145味,包括丹参、麦冬、黄芪等;药物功效有补虚、活血化瘀、清热等。药物隐结构模型得到包括补益肝肾、涩精固脱等4类隐类;症状隐结构模型得到气虚、阴虚、阳虚、痰湿等证素。挖掘出药物-药物频繁项集12项,包括川芎+麦冬+丹参等;药物-证型频繁项集17项,其中包括肉桂+五味子+阴阳两虚等;药物-症状频繁项集12项,包括瓜蒌+大便溏+苔白等。结论 中药辨治糖尿病心脏病以调补心肾、健脾益气为主,并根据具体证型予以用药,可为临床干预糖尿病心脏病提供参考依据。
Abstract:
Abstract:Objective To explore the rule of medication for diabetes heart disease based on modern literature.Methods The literature on the treatment of diabetes and heart disease by traditional Chinese medicine from the establishment of CNKI,CBM and other databases to December 2021 was retrieved.Using Lantern 5.0 and Weka 3.8.5 software respectively,perform hidden structure analysis on drugs and symptoms,as well as frequent itemset analysis on drugs and drugs,drugs and syndrome types,and drugs and symptoms.Results There were a total of 131 references.51 commonly used symptoms in data mining analysis,including white coating,dull complexion,dizziness,etc;145 herbs are used,including Danshen,Ophiopogon japonicus,Astragalus membranaceus,etc;The medicinal effects include tonifying deficiency,promoting blood circulation and removing blood stasis,and clearing heat.The hidden structure model of drugs includes four types of hidden classes: tonifying the liver and kidney,astringent essence and solid removal,etc;The symptom hidden structure model obtains syndrome elements such as Qi deficiency,Yin deficiency,Yang deficiency,and phlegm dampness.Digging out 12 frequent itemsets of drugs,including Chuanxiong,Ophiopogon japonicus,and Salvia miltiorrhiza;The frequent itemset of drug syndrome types includes 17 items,including Cinnamon,Schisandra,Yin Yang deficiency,etc;The drug symptom frequent itemset includes 12 items,including Gualou+loose stools+white coating,etc.Conclusion The treatment of diabetes heart disease with traditional Chinese medicine mainly focuses on regulating the heart and kidney,invigorating the spleen and supplementing Qi,and can be used according to specific syndromes,which can provide reference for clinical intervention of diabetes heart disease.

参考文献/References:

[1]BARZILAY JI,DAVIS BR,GHOSH A,et al.Rapid eGFR change as a determinant of cardiovascular and renal disease outcomes and of mortality in hypertensive adults with and without type 2diabetes[J].J Diabetes Complications,2018,32(9):830-832.
[2]ARNOLD SV,ECHOUFFO-TCHEUGUI JB,LAM CS,et al.Patterns of glucose-lowering medication use in patients with type 2 diabetes and heart failure.Insights from the Diabetes Collaborative Registry(DCR)[J].Am Heart J,2018,203:25-29.
[3]尤良震,潘海娥,代倩倩,等.糖尿病心脏病中医病机述要[J].中医杂志,2021,62(12):1013-1019.
[4]牛明,张斯琴,张博,等.《网络药理学评价方法指南》解读[J].中草药,2021,52(14):4119-4129.
[5]陈丽平,李建生,蔡永敏,等.基于隐结构模型的名老中医辨治京津冀地区慢性支气管炎用药规律研究[J].北京中医药大学学报,2018,41(8):681-688.
[6]FRANK E,HALL M,TRIGG L,et al.DataMining in Bioinformatics using Weka[J].Bioinformatics,2004,20(15):2479-2481.
[7]中华医学会糖尿病学分会.中国2型糖尿病防治指南(2020年版)[J].中华糖尿病杂志,2021,13(4):315-409.
[8]陈贵廷,杨恩澎.实用中西医结合诊断治疗学[M].北京:中国医药科技出版社,1991:339.
[9]苗述楷.糖尿病并发症防治学[M].北京:中国医药科技出版社,2005:115.
[10]陈蔚文.中药学[M].2版.北京:人民卫生出版社,2012.
[11]王永炎.中医内科学[M].上海:上海科学技术出版社,1997:133.
[12]张连文,袁世宏.隐结构模型与中医辨证研究(Ⅰ)——隐结构法的基本思想及隐结构分析工具[J].北京中医药大学学报,2006(6):365-369.
[13]张连文,郭海鹏.贝叶斯网引论[M].北京:科学出版社,2006:227.
[14]GIDEON S.Estimating the dimension of a model[J].Annals of statistics,1978,6(2):461-464.
[15]杨洋,黄启云,刘追星.基于贝叶斯网络之胃癌的辨证标准研究[J].陕西中医药大学学报,2019,42(2):119-126.
[16]FRANK E,HALL M,TRIGG L,et al.Data mining in bioinformatics using Weka[J].Bioinformatics,2004,20(15):2479-2481.
[17]樊一波,文颖娟.糖尿病心肌病中医药治疗刍议[J].陕西中医药大学学报,2018,41(4):123-125,130.
[18]周仲瑛.中医内科学[M].北京:中国中医药出版社,2007.
[19]高怀林.从络论治糖尿病心脏病[J].中国中医基础医学杂志,2012,18(12):1317-1319.
[20]朱棣.普济方[M].北京:人民卫生出版社,1959:2185-2191.
[21]杨雪,杨娟,宋丹,等.基于中医传承辅助平台系统的糖尿病气阴两虚型组方用药规律分析[J].中医临床研究,2017,9(35):4-7.
[22]金鑫.《黄帝内经》脾藏象系统及其疾病名义考辨[D].沈阳:辽宁中医药大学,2017.
[23]陈丽平,蔡永敏,李建生.基于隐结构模型的名老中医诊治慢性支气管炎用药规律探讨[J].中国中药杂志,2017,42(8):1609-1616.
[24]王新佩,贾春华.金匮要略[M].北京:中国中医药出版社,2011:122-123.
[25]吴以岭,高怀林,贾振华,等.糖尿病合并心脏病中医诊疗标准[J].世界中西医结合杂志,2011,6(5):455-460.
[26]孙术宁,黄华鑫,黄超原,等.糖尿病合并冠心病用药规律文献研究[J].中医杂志,2018,59(14):1236-1240.
[27]刘慧敏,郭锦晨,高婷,等.新安医家王任之治疗消渴病经验探析[J].陕西中医药大学学报,2018,41(5):28-30.
[28]马文影.基于数据挖掘及网络药理学探究中医药治疗糖尿病心肌病的用药规律[D].沈阳:辽宁中医药大学,2022.
[29]袁代昌,袁玲,南征,等.《中华医典》治疗消渴用药规律挖掘研究[J].中医药临床杂志,2022,34(2):279-285.
[30]佟奕霖,杨宇峰,石岩.基于中医传承辅助平台的消渴医案用药规律分析[J].辽宁中医杂志,2020,47(7):32-36,221.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金青年基金项目(81603602);安徽省教育厅高校自然科学研究重点项目(KJ2021A0582)
更新日期/Last Update: 2024-05-20