[1]丁超 吴莹 黄欣悦 孙玉 张化为 姜祎 李玉泽 宋小妹 张东东.捆仙七化学成分研究[J].陕西中医药大学学报,2022,(04):032-36.[doi:10.13424/j.cnki.jsctcm.2022.04.007]
　DING Chao WU Ying HUANG Xinyue SUN Yu ZHANG Huawei JIANG Yi LI Yuze SONG Xiaomei ZHANG Dongdong.Study on Chemical Constituents of Kunxianqi[J].Journal of Shaanxi University of Traditional Chinese Medicine,2022,(04):032-36.[doi:10.13424/j.cnki.jsctcm.2022.04.007]
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捆仙七化学成分研究
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《陕西中医药大学学报》[ISSN:2096-1340/CN:61-1501/R]

卷:
期数:
2022年04期
页码:
032-36
栏目:
三秦医药
出版日期:
2022-07-20

文章信息/Info

Title:
Study on Chemical Constituents of Kunxianqi
文章编号:
2096-1340(2022)04-0032-05
作者:
丁超 吴莹 黄欣悦 孙玉 张化为 姜祎 李玉泽 宋小妹 张东东
陕西中医药大学药学院，陕西 咸阳 712046
Author(s):
DING Chao WU Ying HUANG Xinyue SUN Yu ZHANG Huawei JIANG Yi LI Yuze SONG Xiaomei ZHANG Dongdong
College of Pharmacy，Shaanxi University of Chinese medicine，Shaanxi Xianyang 712046,China
关键词:
关键词：捆仙七; 提取分离; 化学成分; 结构鉴定; 脂肪酸
Keywords:
Key words：Kunxianqi; Extraction and separation; Chemical composition; Structural identification; Fatty acid
分类号:
R284.1?
DOI:
10.13424/j.cnki.jsctcm.2022.04.007
文献标志码:
A
摘要:
摘 要：目的 研究捆仙七(Herba pachysandrae terminalis)中的化学成分。方法 采用硅胶、葡聚糖凝胶、反相ODS C18、半制备液相色谱法等色谱技术分离纯化，1D/2DNMR、MS、IR等波谱学技术解析结构。结果 从捆仙七中共分离得到了9个化合物，分别鉴定为4β-methyl-3-methylenepentane-1,2,5triol（1）、4α-methy-3-methylenepentane-1,2,5-triol（2）、magnolioside（3）、香草醛（4）、3，4-二羟基苯甲酸（5）、apocynin（6）、(E)-methyl-12-hydroxyoctadec10Eenoate（7）、(E)-11-hydroxy-octadeca-12-enoic acid（8）、棕榈酸（9）。结论 其中化合物3、6~9为首次从板凳果属中分离得到。
Abstract:
Abstract： Objective To study the chemical constituents of Herba pachysandrae terminalis. Methods Silica gel，dextran gel，reverse phase ODS C18，semi preparative liquid chromatography and other chromatographic techniques were used for separation and purification，and 1D/2D-NMR，MS，IR and other spectroscopy techniques were used to analyze the structure. Results Nine compounds were isolated and identified as 4β-methyl-3-methylenepentane-1,2,5-triol（1），4α-methy-3-methylenepentane1,2,5-triol（2），magnolioside（3），vanillin (4)，3,4dihydroxybenzoic acid (5)，apocynin (6)，(E)-methyl 12-hydroxyladec-10E-enoate (7)，(E)-11-hydroxy-octadeca-12-enoic acid (8)，palmitic acid (9). Conclusion Compounds 3，6~9 were isolated from the genus Stephania for the first time.

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金项目（82104368）；陕西省科技厅自然科学基础研究计划项目（2021JQ-744）；陕西中医药大学研究生创新项目（2021CX06）；陕西中医药大学学科创新团队项目（2019-YL12）
更新日期/Last Update: 2022-07-25