[1]李丽娟 侯政昆 刘凤斌.基于信息熵算法的反流性食管炎用药规律分析[J].陕西中医药大学学报,2019,(05):084-88.[doi:10.13424/j.cnki.jsctcm.2019.05.020]
　Li Lijuan Hou Zhengkun Liu Fengbin.Analysis of the Rule of Medication for Reflux Esophagitis Based on Information Entropy Algorithm[J].Journal of Shaanxi University of Traditional Chinese Medicine,2019,(05):084-88.[doi:10.13424/j.cnki.jsctcm.2019.05.020]
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基于信息熵算法的反流性食管炎用药规律分析()
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《陕西中医药大学学报》[ISSN:2096-1340/CN:61-1501/R]

卷:
期数:
2019年05期
页码:
084-88
栏目:
临床研究
出版日期:
2019-09-16

文章信息/Info

Title:
Analysis of the Rule of Medication for Reflux Esophagitis Based on Information Entropy Algorithm
文章编号:
2096-1340(2019)05-0084-05
作者:
李丽娟1 侯政昆2 刘凤斌2
广州市妇女儿童医疗中心
Author(s):
Li Lijuan 1 Hou Zhengkun 2 Liu Fengbin 2
1. Guangzhou Women and Children’ s Medical Center, Guangzhou China, 510623; 2. The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou China, 510405
关键词:
反流性食管炎; 临床经验; 用药规律; 信息熵
Keywords:
reflux esophagitis;  clinical experience;  rule of medication;  information entropy
分类号:
R256.3
DOI:
10.13424/j.cnki.jsctcm.2019.05.020
文献标志码:
A
摘要:
目的 分析名中医刘凤斌教授治疗反流性食管炎的辩证经验及用药规律。方法 采用回顾性病例研 究，构建病案数据表，运用频数分析、描述性分析、基于信息熵的粗糙集属性约减算法进行用药规律分析。结果 １０８例病例中主要证型有肝胃不和证、肝胃郁热证、脾胃不和证、脾虚湿热证、气阴两虚证；常用药物有白术、茯 苓、海螵蛸、浙贝母等；各证型基于信息熵属性约简的用药子集分别为肝胃不和证（木香、煅赭石、佛手、蒲公英、太 子参）、肝胃郁热证（木香、太子参、大黄、布渣叶、吴茱萸）、脾胃不和证（佛手、蒲公英、太子参、五指毛桃、首乌 藤）、脾虚湿热证（沉香、瓦楞子、紫苏梗、蒲公英、布渣叶）、气阴两虚证（煅赭石、五指毛桃、蒲公英、佛手、熟党 参）。结论 刘教授治疗反流性食管炎用药体现病机特点，注重健脾益气、制酸降逆；结合广东岭南地域特点，运用 广东特色药材清热祛湿；注重调节心理因素影响，重视疏肝解郁安神
Abstract:
Objective To analyze the experience of Professor Liu Fengbin in the treatment of reflux esophagitis and the rule of medication. Methods A retrospective case study was used to construct a medical record data table. Frequency analysis, descriptive analysis and attribute reduction algorithm of rough set based on information entropy were used to analyze the medication rule. Results The main syndromes of 108 cases were liver - stomach disharmony, liver - stomach depression - heat, spleen - stomach disharmony, spleen deficiency - dampness - heat and Qi - Yin deficiency. The commonly used drugs were Atractylodes macrocephala, Poria cocos, cuttlefish, Fritillaria thunbergii and so on. The drug subsets of each syndromes based on information entropy attribute reduction were liver - stomach disharmony ( Aucklandia, calcined ochre, Foshou, Pu) . Dandelion, Radix Pseudostellariae, Liver - stomach Stagnated heat Syndrome ( Muxiang, Radix Pseudostellariae, Rhubarb, Buzao Leaf, Evodia rutaecarpa) , Spleen - stomach Disharmony Syndrome ( bergamot, dandelion, Radix Pseudostellariae, Five - fingered Peach, Polygonum multiflorum) , Spleen Deficiency - damp - heat Syndrome ( Agerate, Corrugated Fructus Perillariae, Dandelion, Buzao Leaf) , Qi - yin Deficiency Syndrome ( Cal Peach,dandelion, bergamot, ripe Codonopsis pilosula. Conclusion Professor Liu＇s medication for reflux esophagitis embodies the characteristics of pathogenesis, pays attention to invigorating the spleen and boosting qi, making acid and reducing adverse reactions; the regional characteristics of Lingnan, Guangdong province is taken into consideration, Guangdong specialty medicinal materials to clear away heat and dampness is used, the attention is paid to regulating the influence of psychological factors, and soothing the liver, relieving depression and tranquillization.

参考文献/References:

[1]侯政昆,李吉平,陈卓群,等.刘凤斌教授治疗胃食管 反流病的病例系列挖掘分析和经验总结[J].中国中 药杂志,2018,43(6):1261-1267
[2]段青青,汪朝惠.埃索美拉唑与奥美拉唑治疗反流性 食管炎的临床对比研究[J].中国医药指南,2018,16 (23):143-144
[3]姜稢琳,胡珂,洪婷,等.基于数据挖掘分析名中医胡 珂治疗胃食管反流病辨证用药规律[J].中医研究, 2018,31(9):55-58
[4]中华中医药学会脾胃病分会.胃食管反流病中医诊疗 专家共识意见(2017)[J].中国中西医结合消化杂 志,2017,25(5):321-327
[5]中华医学会消化内镜学分会.反流性食管炎诊断及治 疗指南(2003年)[J].中华消化内镜杂志,2004,21 (4):221-222
[6]李丽娟.构建重症肌无力五脏相关理论数据挖掘模型 的研究[D].广州:广州中医药大学,2011
[7]时乐,李小飞,单兆伟.单兆伟教授治疗反流性食管炎 临证经验拾萃[J].中国民间疗法,2014,22(12):9-10
[8]樊敏,曾斌芳.反流性食管炎的中医研究进展[J].新 疆中医药,2018,36(3):85-88
[9]叶倩云,陈卓群,杨伟钦,等.基于数据挖掘的刘凤斌 治疗肠易激综合征用药规律分析[J].长春中医药大 学学报,2018,34(2):264-267
[10]谭金华.沈英森教授养胃思想浅述 [J].新中医, 2015,47(7):302-303
[11]刘彦兴.慢性胃炎清热论及用药探析[J].现代中医 药,2018,38(6):114-116
[12]房栋,李亚,刘晓红.中西医结合治疗反流性食管炎 66 例[J].现代中医药,2018,38(5):76-77
[13]吕 景 山.施 今 墨 对 药 [M].北 京:人 民 军 医 出 版 社,2007
[14]张思荻,杨海燕,曾俊,等.佛手的研究进展[J].中华 中医药杂志,2018,33(8):3510-3514
[15]许邹华,陆喜荣,徐倩菲,等.半夏厚朴加瓦楞子汤联 合埃索美拉唑镁治疗胃食管反流随机平行对照研究 [J].实用中医内科杂志,2017,31(12):49-51

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金项目（８１７７４４５０，７１７０４０３１）；广东省科技计划项目（２０１７Ａ０２０２１５１０７
更新日期/Last Update: 2019-09-15