[1]林依娜.中药治疗慢性萎缩性胃炎临床疗效的 Meta分析[J].陕西中医药大学学报,2018,(04):052-58.[doi:10.13424/j.cnki.jsctcm.2018.04.016]
 Lin Yina.Meta Analysis of Clinical Effect of Chinese Medicine in Treating Chronic Atrophic Gastritis[J].Journal of Shaanxi University of Traditional Chinese Medicine,2018,(04):052-58.[doi:10.13424/j.cnki.jsctcm.2018.04.016]
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中药治疗慢性萎缩性胃炎临床疗效的 Meta分析()
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《陕西中医药大学学报》[ISSN:2096-1340/CN:61-1501/R]

卷:
期数:
2018年04期
页码:
052-58
栏目:
临床研究
出版日期:
2018-07-15

文章信息/Info

Title:
Meta Analysis of Clinical Effect of Chinese Medicine in Treating Chronic Atrophic Gastritis
文章编号:
2096-1340(2018)04-0052-07
作者:
林依娜
乌鲁木齐市中医医院,新疆 乌鲁木齐 830000
Author(s):
Lin Yina
TCM Hospital of Urumchi,Xinjiang China,830000
关键词:
中药 中西医 慢性萎缩性胃炎 Meta 分析
Keywords:
Chinese medicine Chinese and western medicine CAG Meta analysis
分类号:
R573. 3 + 2
DOI:
10.13424/j.cnki.jsctcm.2018.04.016
文献标志码:
A
摘要:
目的 中药对慢性萎缩性胃炎治疗的系统评价。方法 按照 Meta 分析方法,借助中国知网、万方等 各大数据库,进行文献搜索,查找关于中药治疗慢性萎缩性胃炎的随机对照试验的相关文献,时间限制在 1997 ~ 2016 年。按照制定的筛选标准确定纳入的文献,将最终纳入的文献进行质量评价,并提取文献中的关于慢性 萎缩性胃炎的临床综合疗效、总体症状体征疗效及胃镜下黏膜的改善情况等治疗数据后,进行数据转换,并采用 ReviewManager5 软件进行 Meta 分析。结果 共纳入 13 个研究,2270 例 CAG 患者。治疗组与对照组相比,临床 综合疗效明显[RR = 1. 22 ,95% CI( 1. 17,1. 27) ,P < 0. 00001],总体的症状体征疗效明显[RR = 1. 68,95% CI [1. 52,1. 86],P < 0. 00001],胃镜表现改善明显[RR = 1. 67,95% CI[1. 40,1. 99],P < 0. 00001],改善病理结局 [RR = 1. 46,95% CI[1. 29,1. 65],P < 0. 00001]。但对于幽门螺杆菌感染阳性者,治疗组与对照组根除效果无统 计学差异。结论 ①对于慢性萎缩性胃炎的治疗,在改善患者症状体征、胃镜表现及病理方面,常规的西医治疗 基础上加用中药治疗较单独使用西药治疗效果更佳。②中西医结合与单独西医治疗在幽门螺旋杆菌根除疗效 方面无显著差异。
Abstract:
To give a systematic evaluation on Chinese medicine in treating chronic atrophic gastritis. Method: In accordance with the Meta analysis method,with the help of CNKI,Wanfang and other major databases,the literature search was conducted to find relevant literature on randomized controlled trials of Chinese medicine for the treat- ment of chronic atrophic gastritis. The time was limited to 1997 - 2016. According to the established selecting criteria to determine the included literature,a quality evaluation was then conducted on the final included literature,and treatment data such as the comprehensive clinical effect of chronic areophic gastritis,the overall symptoms and signs and the im- provement of endoscopic mucosal conditions were extracted and converted,and ReviewManager5 was used for the Meta a- nalysis. Result: A total of 13 studies were included in 2270 CAG cases,Compared with the control group,the clinical comprehensive efficacy of the study group was significant [RR = 1. 22,95% CI( 1. 17,1. 27) ,P < 0. 00001],and the o- verall symptoms and signs were significantly effective [RR = 1. 68,95% CI[1. 52,1. 86],P < 0. 00001],gastroscopy findings improved significantly[RR = 1. 67,95% CI [1. 40,1. 99],P < 0. 00001],pathological outcomes were im- proved [RR = 1. 46,95% CI [1. 29,1. 65],P < 0. 00001]. However,for the positive Helicobacter pylori infection, there was no statistical difference in the eradication effect between the study group and the control group. Conclusion: ( 1) for the treatment of chronic atrophic gastritis,in improving the symptoms and signs,gastroscopy performance and pa- thology of the patients,the traditional Chinese medicine on the basis of traditional western medicine treatment is betterthan the use of western medicine alone. ( 2) there was no significant difference in the eradication efficacy of Helicobacter pylori between traditional Chinese medicine combined with western medicine and western medicine alone.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期: 2018 - 01 - 05 编辑: 文颖绢
更新日期/Last Update: 2019-12-10