[1]汪佩.基于词频分析和共词聚类的大麻素热点问题的研究[J].陕西中医药大学学报,2023,(06):028-35.[doi:10.13424/j.cnki.jsctcm.2023.06.006]
 WANG Pei.Research on Cannabinoids Hotspot Issues Based on???? Word Frequency Analysis and Co Word Clustering[J].Journal of Shaanxi University of Traditional Chinese Medicine,2023,(06):028-35.[doi:10.13424/j.cnki.jsctcm.2023.06.006]
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基于词频分析和共词聚类的大麻素热点问题的研究()
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《陕西中医药大学学报》[ISSN:2096-1340/CN:61-1501/R]

卷:
期数:
2023年06期
页码:
028-35
栏目:
出版日期:
2023-11-20

文章信息/Info

Title:
Research on Cannabinoids Hotspot Issues Based on???? Word Frequency Analysis and Co Word Clustering
文章编号:
2096-1340(2023)06-0028-08
作者:
汪佩
西安开放大学,陕西 西安 710061
Author(s):
WANG Pei
Xi’an Open University,Xi’an 710061,China
关键词:
关键词:大麻素词频分析共词聚类热点问题知识图谱
Keywords:
Key words: CannabinoidsWord frequency analysisCo word clusteringHot topicsKnowledge graph
分类号:
R282.71
DOI:
10.13424/j.cnki.jsctcm.2023.06.006
文献标志码:
A
摘要:
摘?要:以CNKI数据库为数据来源,检索1997年10月—2021年3月以“大麻素”为主题的论文,剔除无关,最终得到898篇文献。利用SATI、UCINET和SPSS 19分别对检索结果进行关键词词频分析、社会网络分析和共词聚类分析。根据大量客观实验数据,揭示了目前国内对大麻素的研究主要集中在大麻素受体、大麻素、内源性大麻素、内源性大麻素系统等方面,通过对其分析研究,为学者们对后续大麻素相关问题的研究提供借鉴和参考。
Abstract:
Abstract: Using the CNKI database as the data source,we searched for papers on the topic of “cannabinoids” from October 1997 to March 2021,excluded irrelevant articles,and ultimately obtained 898 articles.Perform keyword frequency analysis,social network analysis,and co word clustering analysis on the search results using SATI,UCINET,and SPSS 19,respectively.Based on a large amount of objective experimental data,it has been revealed that current research on cannabinoids in China mainly focuses on cannabinoid receptors,cannabinoids,endogenous cannabinoids,endogenous cannabinoid systems,and other aspects.Through analysis and research on them,it provides reference and reference for scholars to study cannabinoid related issues in the future.

参考文献/References:

[1]陈青阳,郑琴,杨明,等.大麻古今临床应用概述[J].江西中医学院学报,2008,20(6):86-88.
[2]Jackson SJ,Diemel LT,Pryce G,et al.Cannabinoids and neuroprotection in CNS inflammatory disease[J].Journal of the Neurological Sciences,2005,233(1/2):21-25.
[3]Falenski KW,Carter DS,Harrison AJ,et al.Temporal characterization of changes in hippocampal cannabinoid CB1 receptor expression following pilocarpine-induced status epilepticus[J].Brain Research,2009,1262:64-72.
[4]Witting A,Chen LF,Cudaback E,et al.Experimental autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection[J].Proceedings of the National Academy of Sciences of the United States of America,2006,103(16):6362-6367.
[5]Loría F,Petrosino S,Mestre L,et al.Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide[J].The European Journal of Neuroscience,2008,28(4):633-641.
[6]Hill MN,Hillard CJ,Bambico FR,et al.The therapeutic potential of the endocannabinoidsystem for the development of a novel class of antidepressants[J].Trends in Pharmacological Sciences,2009,30(9):484-493.
[7]Lutz B.Endocannabinoid signals in the control of emotion[J].Current Opinion in Pharmacology,2009,9(1):46-52.
[8]RomeroZerbo SY,BermúdezSilva FJ.Cannabinoids,eating behaviour,and energy homeostasis[J].Drug Testing and Analysis,2014,6(1/2):52-58.
[9]刘萍,边强.大麻素类药物的治疗作用[J].药学进展,2002,26(2):99-101.
[10]Graham E,Ashton J,Glass M.Cannabinoid Receptors:a brief history and “what & apos;s hot”[J].Frontiers in Bioscience,2009,14(3):944-57.
[11]Moreno E,Andradas C,Medrano M,et al.Targeting CB2GPR55 receptor heteromers modulates cancer cell signaling[J].Journal of Biological Chemistry,2014,289(32):21960-21972.
[12]Pertwee RG.The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids:delta9-tetrahydrocannabinol,cannabidiol and delta9-tetrahydrocannabivarin[J].British Journal of Pharmacology,2008,153(2):199-215.
[13]Ashton JC,Friberg D,Darlington CL,et al.Expression of the cannabinoid CB2 receptor in the rat cerebellum:an immunohistochemical study[J].Neuroscience Letters,2006,396(2):113-116.
[14]Gong JP,Onaivi ES,Ishiguro H,et al.Cannabinoid CB2 receptors:Immunohistochemical localization in rat brain[J].Brain Research,2006,1071(1):10-23.
[15]Baek JH,Zheng YW,Darlington CL,et al.Cannabinoid CB2 receptor expression in the rat brainstem cochlear and vestibular nuclei[J].Acta OtoLaryngologica,2008,128(9):961-967.
[16]Brown AJ.Novel cannabinoid receptors[J].British Journal of Pharmacology,2007,152(5):567-575.
[17]Klumpers LE,Roy C,Ferron G,et al.Surinabant,a selective cannabinoid receptor type 1 antagonist,inhibitsΔ9-tetrahydrocannabinolinduced central nervous system and heart rate effects in humans[J].British Journal of Clinical Pharmacology,2013,76(1):65-77.
[18]Wallace JL,Flannigan KL,McKnight W,et al.Pro’resolution,protective and antinociceptive effects of a Cannabis extract in the rat gastrointestinal tract[J].Journal of Physiology and Pharmacology:an Official Journal of the Polish Physiological Society,2013,64(2):167-175.
[19]那一沙,袁玫,杜修平.基于词频分析和共词聚类的教学设计热点问题的研究[J].现代教育技术,2013,23(3):31-35.
[20]马费成,张勤.国内外知识管理研究热点:基于词频的统计分析[J].情报学报,2006(2):163-171.
[21]钟伟金,李佳,杨兴菊.共词分析法研究(三):共词聚类分析法的原理与特点[J].情报杂志,2008,27(7):118-120.
[22]林聚任.社会网络分析:理论、方法与应用[M].北京:北京师范大学出版社,2009:49-50.
[23]刘启元,叶鹰.文献题录信息挖掘技术方法及其软件SATI的实现:以中外图书情报学为例[J].信息资源管理学报,2012,2(1):50-58.
[24]di Marzo V.CB1 receptor antagonism:biological basis for metabolic effects[J].Drug Discovery Today,2008,13(23/24):1026-1041.
[25]吴永涛.大麻素CB1、CB2受体在脑组织中分布及其表达特性的研究[D].重庆:第三军医大学,2009.
[26]王宇卉,邵福源.大麻素系统及其在神经系统疾病中的治疗前景[J].世界临床药物,2008,29(4):224-228.
[27]Begg M,Pacher P,Bátkai S,et al.Evidence for novel cannabinoid receptors[J].Pharmacology & Therapeutics,2005,106(2):133-145.
[28]唐双奇,陆阳.内源性大麻素—生物合成、信号转导及生物降解[J].中国药理学通报,2013,29(8):1037-1041.
[29]Caulfield MP,Brown DA.Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxinsensitive mechanism[J].British Journal of Pharmacology,1992,106(2):231-232.
[30]Mackie K,Hille B.Cannabinoids inhibit Ntype calcium channels in neuroblastomaglioma cells[J].Proceedings of the National Academy of Sciences of the United States of America,1992,89(9):3825-3829.
[31]Mackie K,Lai Y,Westenbroek R,et al.Cannabinoidsactivate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor[J].The Journal of Neuroscience:the Official Journal of the Society for Neuroscience,1995,15(10):6552-6561.
[32]Deadwyler SA,Hampson RE,Mu J,et al.Cannabinoids modulate voltage sensitive potassium Acurrent in hippocampal neurons via a cAMPdependent process[J].The Journal of Pharmacology and Experimental Therapeutics,1995,273(2):734-743.
[33]Paik HD,ParkJS,Park E.Effects of Bacillus polyfermenticus SCD on lipid and antioxidant metabolisms in rats fed a highfat and highcholesterol diet[J].Biological & Pharmaceutical Bulletin,2005,28(7):1270-1274.
[34]Chen J,Zhang RM,Chen XY,et al.Heterodimerization of human orexin receptor 1 and kappa opioid receptor promotes protein kinase A/cAMP-response element binding protein signaling via a Gαsmediated mechanism[J].Cellular Signalling,2015,27(7):1426-1438.
[35]朱飞,王湘庆,陈亚楠,等.大麻素受体1/食欲素受体1-G蛋白偶联受体异聚体及其交叉激活作用研究进展[J].解放军医学院学报,2015,36(1):94-96.
[36]Seywright A,Torrance HJ,Wylie FM,et al.Analysis and clinical findings of cases positive for the novel synthetic cannabinoid receptor agonist MDMBCHMICA[J].Clinical Toxicology,2016,54(8):632-637.
[37]Giorgetti A,Busardò FP,Tittarelli R,et al.Postmortem toxicology:a systematic review of death cases involving synthetic cannabinoid receptor agonists[J].Frontiers in Psychiatry,2020,11:464.
[38]Wouters E,Walraed J,Banister SD,et al.Insights into biased signaling at cannabinoid receptors:synthetic cannabinoid receptor agonists[J].Biochemical Pharmacology,2019,169:113623.
[39]Eldeeb K,LeoneKabler S,Howlett AC.Cannabinoid receptor antagonists and G protein subtypes[J].The FASEB Journal,2019,33(S1):lb392-lb392.
[40]Porcu A,Melis M,Turecek R,et al.Rimonabant,a potent CB1 cannabinoid receptor antagonist,is a Gαi/o protein inhibitor[J].Neuropharmacology,2018,133:107-120.
[41]Dawidowicz AL,Olszowy-Tomczyk M,Typek R.CBG,CBD,Δ9-THC,CBN,CBGA,CBDA and Δ9-THCA as antioxidant agents and their intervention abilities in antioxidant action[J].Fitoterapia,2021,152:104915.
[42]Robaina Cabrera CL,Keir-Rudman S,Horniman N,et al.The anti’inflammatory effects of cannabidiol and cannabigerol alone,and in combination[J].Pulmonary Pharmacology & Therapeutics,2021,69:102047.
[43]Zhou C,Assareh N,Arnold JC.The Cannabis constituent cannabigerol does not disrupt fear memory processes or stressinduced anxiety in mice[J].Cannabis and Cannabinoid Research,2021:2021 Jun 28.
[44]佚名.我国成为全球首个整类列管合成大麻素类物质的国家[J].中国法医学杂志,2021,36(3):317.

备注/Memo

备注/Memo:
基金项目:国家自然科学基金青年项目(82004489)
更新日期/Last Update: 2023-11-24