[1]吕继宏 段玉红 张效科 苏虹霞 苏露煜 王黎 巩雪莹 刘爱霞.香砂六君子汤治疗糖尿病胃轻瘫脾胃气虚兼痰湿气滞型临床研究[J].陕西中医药大学学报,2023,(04):044-50.[doi:10.13424/j.cnki.jsctcm.2023.04.008]
　LYU Jihong DUAN Yuhong ZHANG Xiaoke SU Hongxia SU Luyu WANG Li GONG Xueying LIU Aixia.Clinical Study on Xiangsha Liujunzi Decoction in Treating Diabetes Gastroparesis with Spleen Stomach Qi Deficiency and Phlegm Dampness Qi Stagnation Type[J].Journal of Shaanxi University of Traditional Chinese Medicine,2023,(04):044-50.[doi:10.13424/j.cnki.jsctcm.2023.04.008]
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香砂六君子汤治疗糖尿病胃轻瘫脾胃气虚兼痰湿气滞型临床研究()
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《陕西中医药大学学报》[ISSN:2096-1340/CN:61-1501/R]

卷:
期数:
2023年04期
页码:
044-50
栏目:
出版日期:
2023-07-20

文章信息/Info

Title:
Clinical Study on Xiangsha Liujunzi Decoction in Treating Diabetes Gastroparesis with Spleen Stomach Qi Deficiency and Phlegm Dampness Qi Stagnation Type
文章编号:
2096-1340(2023)04-0044-07
作者:
吕继宏1 段玉红1 张效科2 苏虹霞1 苏露煜1 王黎1 巩雪莹1 刘爱霞1
1.陕西中医药大学附属医院,陕西 咸阳 712000，
2.陕西中医药大学,陕西 咸阳 712046
Author(s):
LYU Jihong1 DUAN Yuhong1 ZHANG Xiaoke2 SU Hongxia1 SU Luyu1 WANG Li1 GONG Xueying1 LIU Aixia1
1.Affiliated Hospital of Shaanxi University of Chinese Medicine,Shaanxi Xianyang 712000,China;
2.Shaanxi University of Chinese Medicine,Shaanxi Xianyang 712000,China
关键词:
关键词：香砂六君子汤; 糖尿病胃轻瘫; 消渴; 痞满; 糖代谢
Keywords:
Key words： Xiangsha Liujunzi decoction; Diabetes gastroparesis; Quench thirst; Distention and fullness; Sugar metabolism
分类号:
R587.2
DOI:
10.13424/j.cnki.jsctcm.2023.04.008
文献标志码:
A
摘要:
摘 要：目的 探讨香砂六君子汤治疗脾胃气虚兼痰湿气滞型糖尿病胃轻瘫的临床疗效及其与糖代谢等指标的相关性。方法 将2022年1月—2022年12月就诊于陕西中医药大学附属医院的80例脾胃气虚兼痰湿气滞型糖尿病胃轻瘫患者随机分为治疗组40例和对照组40例。对照组予口服多潘立酮片治疗，治疗组在对照组治疗的基础上加用中药汤剂香砂六君子汤，2组疗程均为3个月。对比2组患者治疗前后临床症状评分、糖代谢指标（空腹血糖、餐后2小时血糖、糖化血红蛋白）、血清胃肠道激素指标（胃泌素-17）、营养情况指标水平（白蛋白、血红蛋白）变化情况。结果 治疗后2组患者临床症状评分、糖代谢指标、胃肠激素指标、营养情况指标均较治疗前改善，且治疗组优于对照组，差异有统计学意义（P<0.05）；进一步的相关分析及回归分析表明患者临床症状缓解程度与糖化血红蛋白呈负相关，与白蛋白呈正相关（P<0.05）。结论 香砂六君子汤可以很好的改善脾胃气虚兼痰湿气滞型糖尿病胃轻瘫患者的临床症状及营养情况，纠正糖代谢紊乱，调节胃肠道激素，促进胃肠道功能的恢复。
Abstract:
Abstract： Objective To explore the clinical efficacy of Xiangsha Liujunzi decoction in the treatment of diabetes gastroparesis with spleen stomach Qi deficiency and phlegm dampness Qi stagnation and its correlation with glucose metabolism and other indicators.Methods From January 2022 to December 2022,80 patients with diabetes gastroparesis of spleen stomach Qi deficiency and phlegm dampness Qi stagnation type who were hospitalized in the affiliated hospital of Shaanxi University of Chinese Medicine were randomly divided into the treatment group of 40 cases and the control group of 40 cases.The control group was treated with oral Domperidone tablets,and the treatment group was treated with Xiangsha Liujunzi decoction,a traditional Chinese medicine decoction,on the basis of the treatment of the control group.The course of treatment of both groups was 3 months.The clinical symptom scores,glucose metabolism indexes (Fasting blood sugar,2hour postprandial blood glucose,Glycated hemoglobin),serum gastrointestinal hormone indexes (gastrin-17),and nutritional status index levels (albumin,hemoglobin) of the two groups were compared before and after treatment.Results After treatment,the clinical symptom scores,glucose metabolism indicators,gastrointestinal hormone indicators,and nutritional status indicators of the two groups of patients improved compared to before treatment,and the treatment group was better than the control group,with a statistically significant difference (P<0.05);Further correlation analysis and regression analysis showed that the degree of clinical symptom relief was negatively correlated with Glycated hemoglobin and positively correlated with albumin (P<0.05).Conclusion Xiangsha Liujunzi decoction can improve the clinical symptoms and nutritional status of diabetes gastroparesis patients with spleen stomach Qi deficiency and phlegm dampness Qi stagnation,correct the disorder of glucose metabolism,regulate gastrointestinal hormones,and promote the recovery of gastrointestinal function.

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金项目(81774304)
更新日期/Last Update: 2023-07-29