[1] U Jing XU Xia SUN Guanghan LI Xiao NAN Gao XU Yuan ZHU Jun LIU Junlan,.Characteristics of Bi Syndrome Medication and Prescription Rules in Jing Yue Quan Shu Based on Data Analysis [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2024, (04): 66-71. [doi: 10.13424/j.cnki.jsctcm.2024.04.014]
Characteristics of Bi Syndrome Medication and Prescription Rules in Jing Yue Quan Shu Based on Data Analysis
- Article number:
- 2096-1340(2024)04-0066-06
- Keywords:
- Key words： Jing Yue Quan Shu; ZHANG Jiebin; Bi syndrome; Data analysis; Medication characteristics; Formation rules
- ZTFLH:
- R255.6
- Code:
- A
- Abstract:
- Abstract： Objective To use data mining techniques to explore the medication characteristics and formula rules reflected in the internal medication of Jing Yue Quan Shu for treating Bi syndrome，and to inspire modern clinical formula medication ideas.Methods By organizing and summarizing the drugs involved in the internal treatment of Bi in Jing Yue Quan Shu，the frequency of the drugs used in the internal treatment of Bi in Jing Yue Quan Shu was statistically analyzed using Microsoft Excel (2019).The Apriori algorithm in IBM SPSS 25.0 and IBM SPSS Modeler 18.0 were used for cluster analysis and association rule analysis to explore the characteristics of ZHANG Jiebin’s medication for treating Bi and his formulation ideas.Results There were a total of 94 prescriptions for treating Bi in Jing Yue Quan Shu，involving 140 types of drugs and a total of 794 times of medication used;The top 15 medicines with the highest frequency of use are licorice，Angelica sinensis，Ligusticum chuanxiong，Poria cocos，Fangfeng，Qianghuo，Atractylodes macrocephala，Cinnamomum cassia，Achyranthes bidentata，Ginseng，Rehmannia glutinosa，Aconite，Chenpi，White Peony，and Atractylodes macrocephala;The drugs used are mainly warm drugs，with a main pungent taste，mainly targeting the spleen (stomach) meridian.The total frequency of using tonifying deficiency drugs is the highest;Cluster analysis was conducted on the top 46 drugs with the highest frequency of use，resulting in 18 drug combinations including Fructus Aurantii，Platycodon grandiflorus，Chenpi Pinellia ternata，Betel nut，and Perilla leaves;An association rule analysis was conducted on the top 46 drugs with the highest frequency of use，and 13 drug combinations were obtained，including licorice-ginseng-Poria cocos，licorice-ginseng-Atractylodes macrocephala，Angelica sinensis-Rehmannia-Ligusticum chuanxiong.Conclusion ZHANG’s treatment of Bi emphasizes nourishing the liver and kidney，nourishing the true Yin，and emphasizes the elimination of cold pathogenic factors based on syndrome differentiation.He is skilled in strengthening the spleen and tonifying Qi，regulating the Qi activity to eliminate the pathogenic factors of phlegm and dampness，and emphasizes the use of blood activating and stasis resolving drugs.
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Memo
基金项目：2020年度国家中医药管理局“中医药古籍文献和特色技术传承专项”（GZY-KJS-2020-044）