[1] LI Juan ZHAN Junjie HUANG Hui GAO Bing JIANG Haitao YU Miaomiao JIAO Zhiyu,.Study on Drug Use Rule of Three Representative Physiciansof Xin'an Guben Peiyuan School in Treatment of Acne [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2023, (01): 66-75. [doi: 2096-1340(2023)01-0066-10]
Study on Drug Use Rule of Three Representative Physicians
of Xin'an Guben Peiyuan School in Treatment of Acne
- Article number:
- 10.13424/j.cnki.jsctcm.2023.01.013
- ZTFLH:
- R272.2
- Code:
- A
- Abstract:
- Abstract：Objective To study the rule of drug use in the treatment of acne by three representative physicians of Guben Peiyuan School of Xinan in order to guide clinical practice.Methods Microsoft Excel 2019 system，SPSS Modeler 18.0 system and SPSS Statistics 25.0 system were used to analyze and summarize the commonly used drugs and drug use rules of three representative physicians of Guben Peiyuan School of Xin'an，and compare the similarities and differences in drug use of three Xinan physicians in the treatment of acne.Results A total of 719 prescriptions were selected for the treatment of acne from WANG Ji's Dou Zhi Li Bian，XU Chunfu's Dou Zhen Xie Mi and SUN Yikui's Dou Zhen Xin Yin.The 290 drugs in the prescription were divided into 18 categories，and most of the three physicians'drugs were drugs for tonifying deficiency，clearing heat and relieving symptoms.There were 292 prescriptions screened in WANG Ji's Dou Zhi Li Bian，and 198 drugs appeared in total.XU Chunfu selected 126 prescriptions in Dou Zhen Xie Mi，and 146 drugs were found in total.SUN Yikui screened 301 prescriptions in his Dou Zhen Xin Yin，and 222 medicines appeared.The four herbs with the highest medication frequency were Licorice，Ginseng，Angelica and Atractylodes macrocephala.The systematic cluster analysis was carried out on three Xin'an doctors for the treatment of acne，and nine cluster combinations were obtained.In the association rule analysis，the three Xin'an physicians ranked first in two association analysis，namely，Licorice-Ginseng，Ginseng-Jujube，and Licorice Astragalus.Conclusion The three physicians of the School of Strengthening the Foundation and Cultivating the Yuan have all practiced the idea of strengthening the foundation and cultivating the Yuan in treating acne，and put the strengthening of the spleen and stomach and the strengthening of the spleen and Qi at an important position.At the same time，according to the pathogeny and pathogenesis characteristics of acne disease，the treatment by stages adopted methods such as relieving exterior，harmonizing middle and detoxification，which have clinical guiding significance for modern prevention and treatment of acne like infectious diseases.
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Memo
基金项目：2020年安徽省高校协同创新项目:(GXXT-2020-037)；2021年安徽中医药大学省级大学生创新创业训练项目(S202110369131)