[1] Lei Jingyi, Cheng Huyin, Zhang Yixiao, et al. A Pharmacognostic Study of Changyao Gezhonglou in Shaanxi [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2020, (6): 36-43. [doi: 10.13424/j.cnki.jsctcm.2020.06.010]
A Pharmacognostic Study of Changyao Gezhonglou in Shaanxi
- Article number:
- 2096-1340(2020)06-0036-08
- Keywords:
- changyao gezhonglou in Shaanxi; growth characteristics; pharmacognosy; microscopic structure; polyphyllin
- ZTFLH:
- R282.71
- Code:
- A
- Abstract:
- Objective To make a research on pharmacognosical characteristics of crude medicine rhizome of changyao gezhonglou( var. pseudothibetica H. Li) in Shaanxi. Methods The morphological feature of original plant, pharmacognostic and microscopical characteristics of crude medicine rhizome of changyao gezhonglou in Shaanxi are studied by morphological and histological identification. HPLC was adopted in the determination of quality control class effective components of the total content of 4 saponins( polyphyllinⅠ, Ⅱ, Ⅵ, Ⅶ) . Results Changyao gezhonglou in Shaanxi has specific growth characteristics, the root and stem have microscopic characteristics. There are one layer of suberification epidermis, cortex and discontinuous remarkable endodermis, and some stele of amphivasal vascular bundle in the parenchyma tissue which were observed in the transection section. In the crude drug powder, the powder contains a lot of single - grain starch andcalcium oxalate needle crystals, threads and trapezoidal catheters. In addition, the total content of 4 saponins reaches up to 1. 086% with HPLC. Conclusion PPT from Shaanxi Province have definite origin sources, stable pharmacognosical characteristics, specific microstructures, and high content of 4 saponins. The results elucidate that the combining rhizome of changyao gezhonglou with zhonglou of Chinese medicine among common people is reasonable to some extent, laying a foundation for standardizing the quality and developing resources of changyao gezhonglou in Shaanxi.
References:
[1]中国科学院中国植物志编辑委员会.中国植物志15[M].北京:科学出版社,1978:88-96.
[2]程虎印,颜永刚,刘亮亮,等.陕产重楼属南重楼组药用植物类群及资源调查[J].中国中医药信息杂志,2018,25(3):1-6.
[3]蒋露,康利平,刘大会,等.历代本草重楼基原考[J].中国中药杂志,2017,42(18):3469-3473.
[4]王跃虎,牛红梅,张兆云,等.重楼属植物的药用价值及其化学物质基础[J].中国中药杂志,2015,40(5):833-839.
[5]杨德全,杨勤,周浓.多基源重楼的质量等同性研究[J].中国实验方剂学杂志,2014,20(3):91-94.
[6]杨远贵,张霁,张金渝,等.重楼属植物化学成分及药理活性研究进展[J].中草药,2016,47(18):3301-3323.
[7]刘湘丹,王朝辉,徐玉琴,等.中药材重楼研究进展[J].中医药导报,2015,20(15):90-93.
[8]王薛,陈卓,尹鸿翔.重楼在中国民族民间医药中的应用[J].华西药学杂志,2018,33(5):555-560.
[9]王娟,尹博睿,何燕.重楼属植物的本草学和民族植物学研究[J].云南中医中药杂志,2017,38(5):80-82.
[10]张亚茹,彭献娜,王彩虹,等.重楼活性化学成分与药理作用研究进展[J].亚太传统医药,2015,11(2):39-40.
[11] Shull Man, Hongyuan Chai, Jingxia Cui, Jingwen Yao, Long Ma,Wenyuan Gao. Antitumor and anti - metastatic mechanisms of Rhizoma paridis saponins in Lewis mice. [ J] . Environmental Toxicology, .2018,3( 2) : 149 -155.
[12]赵飞亚,陶爱恩,夏从龙.基于国内专利结合资源?应用与开发现状的重楼发展策略探讨[J].中国中药杂志,2018,43(2):404-409.
[13]国家药典委员会编.中华人民共和国药典一部(2015版)[S].北京:中国医药科技出版社,2015:260.
[14]程虎印,刘亮亮,程江雪,等.华阴市产重楼属药用植物生态特点及资源状况调查[J].中国现代应用药学,2017,34(5):674-680.
[15]杨光义,胡培,叶方,等.重楼资源分布与可持续利用研究进展[J].中国药师,2016,19(1):159-162.
[16]成莉,甄艳,陈敏,等.扩大重楼药用资源研究进展[J].中国中药杂志,2015,40(16):3121-3124.
[17]程虎印,程江雪,王艳,等.宽叶重楼的生药学研究[J].中国现代中药,2019,21(1):1480-1485.
[18]程虎印,杨哲,程江雪,等.陕产具柄重楼的生药学研究[J].中医药导报,2019,25(7):39-44.
[19]赵志勇,高文远,黄贤校,等.长药隔重楼化学成分研究[J].中草药,2011,42(10):1917-1920.
[20]刘显波,张浩,雍正平,等.长药隔重楼中甾体皂苷成分的分离与结构鉴定[J].华西药学杂志,2010,25(5):508-511.
[21]程虎印,王艳,赵乐,等.基于高通量测序揭示重楼根际土及不同部位真菌群落差异[J].药物分析杂志,2020,40(3):455-461.
[22]程虎印,徐进,颜永刚,等.陕产重楼属药用植物的研究进展[J].陕西中医药大学学报,2017,40(1):107-111.
[23]黄璐琦,肖培根,王永炎.中国珍稀濒危药用植物资源调查[M].上海:上海科学技术出版社,2012:148-164.
[24]宋小妹,刘海静.太白七药研究与应用[M].北京:人民卫生出版社,2011:132-137.
[25]高妍,李德旺,过立农,等.基于国家药品评价性抽验的全国重楼饮片质量情况分析与研究[J].中国药事,2019,33(7):754-759.
[26]李太兵.中药名称规范化研究[J].亚太传统医药,2014,10(4):8-9.
[27]程虎印,王薇,程江雪.“七药”的资源特征及其研发策略[J].中草药,2014,45(15):2272-2276.
[28]肖培根.新编中药志1[M].北京:化学工业出版社,2002:704-713.
[29]中国药材总公司.中国中药区划[M].北京:科学出版社,1995:312-316.
[30]李恒,陈昌祥,丁靖凯.重楼属植物的化学成分?地理分布及资源评价[J].云南植物研究,1988,增刊I:38-46.
[31]朱涛,张云,岳显可,等.在法定标准中谨慎扩大部分中药来源的可行性研究[J].中国现代应用药学,2019,36(1):90-93.
[32]张海珠,赵飞亚,陶爱恩,等.基于成分-活性整体相似性的重楼替代资源筛选[J].中草药,2018,49(18):4366-4373.
[33]王鑫,王艳翠.中药标准化问题与对策研究[J].中华中医药杂志,2018,33(1):22-25.
[34]陕西省食品药品监督管理局陕西省中药饮片标准[S].西安:陕西科学技术出版社,2008.
[35]陕西省食品药品监督管理局陕西省药材标准(2015年版)[S].西安:陕西科学技术出版社,2016.
Memo
基金项目:国家重点研发计划项目(2018YFD1001000);陕西中医药大学2019年省级大创项目(S201910716038);陕西省科学院科技计划项目(2018nk-01)
通讯作者:程虎印,教授?E-mail:Huyin_Cheng@126.com