[1] Zhang Xiucheng, Zhang Jinbo, Gao Xinghua, et al. A Correlational Research on the Syndromes and Micro - differentiation of Covid -19 in 35 Cases [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2020, (4): 1-5. [doi: 10.13424/j.cnki.jsctcm.2020.04.001]
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Journal of Shaanxi University of Traditional Chinese Medicine[ISSN: 2096-1340/ CN: 61-1501/R]
Volumes & Issues:
2020 No.4
pagination:
1-5
Column:
Publication date:
2020-07-15
- Article number:
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2096-1340(2020)04-0001-05
- Author(s):
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Zhang Xiucheng; Zhang Jinbo; Gao Xinghua; Zhang Xiyi; Gong Xianfeng
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Xi’an Chest Hospital, Xi’an Shaanxi 710000
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- Keywords:
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Covid -19; TCM; syndromes; micro - differentiation; a correlative research
- ZTFLH:
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563.1
- DOI:
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10.13424/j.cnki.jsctcm.2020.04.001
- Code:
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A
- Abstract:
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Objective To explore the correlation between the syndromes and the micro - differentiation of Covid -19 by analyzing its clinical syndromes, therapy and prescription as well as laboratory examinationin in 35 cases. Method 35 cases with Covid -19 are collected to examine their symptoms, tongue manifestation, syndromes, prescriptions, laboratory test and curative effect, then the data analysis and statistical process are made. Result Among 35 cases, a majority of patients show mild symptoms. 20 cases are characterized by “ the cold - dampness restraining the exterior and hot stasis harming the fluid” syndromes, 6 cases with “ the wind - coldness invading the exterior and the damp - stasis caused by qi deficiency” syndromes, 7 cases with “ the hot toxin invading the lung” syndromes, and 2 cases with hot toxin obstructing the lung” syndromes. After the laboratory test, the comparison of lymphocyte count among different syndromes shows statistically significant difference ( P < 0. 05) . The lymphocyte count of patients with ‘ the hot toxin obstructing the lung” syndromes are lower than those with “ the cold - dampness restraining the exterior and hot stasis harming the fluid” syndromes( P <0. 05) . There was no difference in white blood cell count, erythrocyte sedimentation rate, and c – reactive protein ( P >0. 05) , but erythrocyte sedimentation rate and c - reactive protein were generally increased among different syndromes. The statistical results of T lymphocyte analysis in 23 cases show that total T lymphocyte ( CD 3 + ) was different among different syndromes ( P < 0. 05) . However, there is no difference in T - helper lymphocytes ( CD 3 + , CD 4 + ) and T - inhibitory lymphocytes ( CD 3 + , CD 8 + ) ( P > 0. 05) . The total T lymphocytes ( CD 3 + ) of patients with “ the cold - dampness restraining the exterior and hot stasis harming the fluid” syndromes are significantly higher than those with “ the wind - coldness invading the exterior and the damp - stasis caused by qi deficiency” syndromes( P <0.05) , and the difference is statistically significant. In terms of the evaluation of curative effect, the main symptom improvement time was ( 4. 85 ±3. 40) days, the average hospital stay was ( 17. 74 ±4. 92) days, and the clinical cure rate was 94. 29%. Conclusion The basic pathogenesis of Covid -19 inclues the dampness, coldness, heat, toxin and stasis, therefore prescriptions like Huoxiang Zhengqi Powder, Ganlu Xiaodu Pill, Yinqiao Powder, Maxing Ganshi Decoction are used frequently. In all, the treatment of Covid -19 is highly effective if the Western and Chinese Medicine are attached equal importance, combining with the micro - differentiation.
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