[1] CHEN LixiaGUO MiaomiaoLI RutingPENG JianfeiZHANG HuilingWANG LiangSHI Hui,.Analysis on Medication Rule of Diabetes Heart Disease Treated by Traditional Chinese Medicine [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2024, (03): 74-81. [doi: 10.13424/j.cnki.jsctcm.2024.03.011]
Analysis on Medication Rule of Diabetes Heart Disease Treated by Traditional Chinese Medicine
- Article number:
- 2096-1340(2024)03-0074-08
- Keywords:
- Key words：Diabetes; Heart disease; Data mining; Hidden structure; Frequent itemsets; Medication patterns
- ZTFLH:
- R259
- Code:
- A
- Abstract:
- Abstract：Objective To explore the rule of medication for diabetes heart disease based on modern literature.Methods The literature on the treatment of diabetes and heart disease by traditional Chinese medicine from the establishment of CNKI,CBM and other databases to December 2021 was retrieved.Using Lantern 5.0 and Weka 3.8.5 software respectively,perform hidden structure analysis on drugs and symptoms,as well as frequent itemset analysis on drugs and drugs,drugs and syndrome types,and drugs and symptoms.Results There were a total of 131 references.51 commonly used symptoms in data mining analysis,including white coating,dull complexion,dizziness,etc;145 herbs are used,including Danshen,Ophiopogon japonicus,Astragalus membranaceus,etc;The medicinal effects include tonifying deficiency,promoting blood circulation and removing blood stasis,and clearing heat.The hidden structure model of drugs includes four types of hidden classes: tonifying the liver and kidney,astringent essence and solid removal,etc;The symptom hidden structure model obtains syndrome elements such as Qi deficiency,Yin deficiency,Yang deficiency,and phlegm dampness.Digging out 12 frequent itemsets of drugs,including Chuanxiong,Ophiopogon japonicus,and Salvia miltiorrhiza;The frequent itemset of drug syndrome types includes 17 items,including Cinnamon,Schisandra,Yin Yang deficiency,etc;The drug symptom frequent itemset includes 12 items,including Gualou+loose stools+white coating,etc.Conclusion The treatment of diabetes heart disease with traditional Chinese medicine mainly focuses on regulating the heart and kidney,invigorating the spleen and supplementing Qi,and can be used according to specific syndromes,which can provide reference for clinical intervention of diabetes heart disease.
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Memo
基金项目：国家自然科学基金青年基金项目(81603602)；安徽省教育厅高校自然科学研究重点项目(KJ2021A0582)