[1] HU JianweiDING ChaoWU YingZHANG Yuying GONG ChuanmingZHANG DongdongWANG Wei,.Research Progress on the Treatment of Rheumatoid Arthritis with Sinomenine and Its Preparations [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2024, (03): 1-7. [doi: 10.13424/j.cnki.jsctcm.2024.03.001]
Research Progress on the Treatment of Rheumatoid Arthritis with Sinomenine and Its Preparations
- Article number:
- 2096-1340(2024)03-0001-07
- ZTFLH:
- R285.6
- Code:
- A
- Abstract:
- Abstract： Rheumatoid arthritis (RA) is an autoimmune disease with a high incidence rate,which tends to occur in middle-aged women and seriously affects the motor ability of patients.At present,the pathogenesis of the disease is not fully understood,and existing treatment plans only focus on delaying the condition and improving joint function.Qingteng alkaloid is an effective ingredient in Qingfengteng,which has various pharmacological activities such as anti-inflammatory,analgesic,immunosuppressive,anti-tumor,etc.It is quite effective in the treatment of rheumatoid arthritis,mainly by alleviating inflammation,inhibiting periosteal proliferation,reducing bone damage,and the combined use of drugs has a better effect.Nowadays,there are also many compound preparations related to sinomenine on the market,such as Qubi Huoluorecipe,Qinxitong tablet,etc.,all of which have shown good anti RA effects with minimal adverse reactions.Therefore,based on the relevant research on the anti RA effect of sinomenine,this article reviews the mechanism of action and compound preparations of sinomenine in the treatment of rheumatoid arthritis,in order to provide reference for its future development and utilization.
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Memo
基金项目：国家自然科学基金项目（82104368）；陕西中医药大学创新团队项目（2023-CXTD-05）