[1] CHEN Jin WANG Yunfeng ZHAO RuiruiZHENG YanxiaZHANG Ying,.Effectiveness of Qingfei Huatan Decoction in Treating Bronchopneumonia [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2023, (05): 94-98. [doi: 10.13424/j.cnki.jsctcm.2023.05.015]
Effectiveness of Qingfei Huatan Decoction in Treating Bronchopneumonia
- Article number:
- 20961340(2023)05-0094-05
- Keywords:
- Key words： Qingfei Huatan decoction; Oxidative stress; Lung function; Bronchopneumonia; Randomized control; Inflammatory factors
- ZTFLH:
- R256.1
- Code:
- A
- Abstract:
- Abstract： Objective To explore the effects of Qingfei Huatan decoction on lung function,oxidative stress indicators,and inflammatory factors in patients with bronchopneumonia.Methods A total of 80 patients with bronchopneumonia admitted to our hospital from April 2021 to May 2022 were collected and randomly divided into control group (40 cases,treated with conventional Western medicine) and treatment group (40 cases,treated with conventional Western medicine and Qingfei Huatan decoction).Clinical efficacy was evaluated,serum inflammatory factors,lung function,oxidative stress indicators were measured before and after treatment,and adverse reactions were recorded.Results The total effective rate of the treatment group was higher than that of the control group (P<0.05);After treatment,the levels of serum interleukin-6 (IL-6) and C-reactive protein (CRP) in the treatment group were significantly lower than those in the control group (P<0.05);After treatment,the first second forced expiratory volume (FEV1) and forced vital capacity (FVC) of the treatment group were significantly higher than those of the control group (P<0.05);After treatment,the serum levels of malondialdehyde (MDA) in the treatment group were significantly lower than those in the control group,while the levels of superoxide dismutase (SOD) were higher than those in the control group (P<0.05);There was no significant difference in the incidence of adverse reactions between groups (P>0.05).Conclusion Treating patients with bronchopneumonia with Qingfei Huatan decoction can downregulate serum inflammatory factor levels,alleviate oxidative stress damage,improve lung function,and show no increase in adverse reactions.
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Memo
基金项目：榆林市科技计划项目（YF-2020-068）