[1] LYU Jihong DUAN Yuhong ZHANG Xiaoke SU Hongxia SU Luyu WANG Li GONG Xueying LIU Aixia,.Clinical Study on Xiangsha Liujunzi Decoction in Treating Diabetes Gastroparesis with Spleen Stomach Qi Deficiency and Phlegm Dampness Qi Stagnation Type [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2023, (04): 44-50. [doi: 10.13424/j.cnki.jsctcm.2023.04.008]
Clinical Study on Xiangsha Liujunzi Decoction in Treating Diabetes Gastroparesis with Spleen Stomach Qi Deficiency and Phlegm Dampness Qi Stagnation Type
- Article number:
- 2096-1340(2023)04-0044-07
- Keywords:
- Key words： Xiangsha Liujunzi decoction; Diabetes gastroparesis; Quench thirst; Distention and fullness; Sugar metabolism
- ZTFLH:
- R587.2
- Code:
- A
- Abstract:
- Abstract： Objective To explore the clinical efficacy of Xiangsha Liujunzi decoction in the treatment of diabetes gastroparesis with spleen stomach Qi deficiency and phlegm dampness Qi stagnation and its correlation with glucose metabolism and other indicators.Methods From January 2022 to December 2022,80 patients with diabetes gastroparesis of spleen stomach Qi deficiency and phlegm dampness Qi stagnation type who were hospitalized in the affiliated hospital of Shaanxi University of Chinese Medicine were randomly divided into the treatment group of 40 cases and the control group of 40 cases.The control group was treated with oral Domperidone tablets,and the treatment group was treated with Xiangsha Liujunzi decoction,a traditional Chinese medicine decoction,on the basis of the treatment of the control group.The course of treatment of both groups was 3 months.The clinical symptom scores,glucose metabolism indexes (Fasting blood sugar,2hour postprandial blood glucose,Glycated hemoglobin),serum gastrointestinal hormone indexes (gastrin-17),and nutritional status index levels (albumin,hemoglobin) of the two groups were compared before and after treatment.Results After treatment,the clinical symptom scores,glucose metabolism indicators,gastrointestinal hormone indicators,and nutritional status indicators of the two groups of patients improved compared to before treatment,and the treatment group was better than the control group,with a statistically significant difference (P<0.05);Further correlation analysis and regression analysis showed that the degree of clinical symptom relief was negatively correlated with Glycated hemoglobin and positively correlated with albumin (P<0.05).Conclusion Xiangsha Liujunzi decoction can improve the clinical symptoms and nutritional status of diabetes gastroparesis patients with spleen stomach Qi deficiency and phlegm dampness Qi stagnation,correct the disorder of glucose metabolism,regulate gastrointestinal hormones,and promote the recovery of gastrointestinal function.
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Memo
基金项目：国家自然科学基金项目(81774304)