[1] LI Shixing CHEN Xiaolin ZHANG Huawei DENG Chong SONG Xiaomei ZHANG Dongdong WANG Wei LI Yuze,.Research Progress on Chemical Composition，Pharmacological Action and Quality Control of Hongsuanqi [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2023, (01): 12-18. [doi: 10.13424/j.cnki.jsctcm.2023.01.003]
Research Progress on Chemical Composition，Pharmacological Action and Quality Control of Hongsuanqi
- Article number:
- 2096-1340(2023)01-0012-07
- ZTFLH:
- R282.71
- Code:
- A
- Abstract:
- Abstract：Hongsuanqi is a liliaceae plant oil herb Tricyrtis macropoda Miq and the root or whole grass of Tricyrtis pilosa Wallich，which is one of the seven medicines of Taibai.The research shows that the main chemical components of Hongsuanqi are flavonoids，lignans and steroids，which have the pharmacological effects of anti thrombosis，anti inflammation and antioxidation.In this paper，the chemical composition，pharmacological action and quality control of Hongsuanqi are reviewed in order to provide reference for further research，development and utilization.
References:
［1］中国科学院中国植物志编辑委员会.中国植物志（18卷）［M］.北京:科学出版社,1999.
［2］杨健.四种太白山药用植物的化学成分研究［D］.杨凌:西北农林科技大学,2011.
［3］国家中医药管理局《中华本草》编委会.中华本草·傣药卷［M］.上海:上海科学技术出版社,2005.
［4］张勤.黄瓜香的形态组织鉴定［J］.中草药,2000,31(8):622-624.
［5］陕西省食品药品监督管理局.陕西省药材标准［S］.2015年版.西安:陕西科学技术出版社,2016:50-51.
［6］李密密,耿茂林,徐增莱,等.一种黄花油点草的扦插繁殖方法:中国，110558073A［P］.2019-12-13.
［7］宋小妹,刘海静.太白七药研究与应用［M］.北京:人民卫生出版社,2011.
［8］孙静,刘洁琼,张丽梅.陕产黄花油点草化学成分初步研究［J］.陕西中医,2012,33(5):605-606.
［9］孙冬梅.红酸七化学成分的研究［D］.杨凌:西北农林科技大学,2010.
［10］王赟泽.陕产黄花油点草物质基础与活血作用研究［D］.咸阳:陕西中医药大学,2021.
［11］杨洁,张东东,张欣,等.黄花油点草化学成分研究［J］.中南药学,2017,15(7):922-924.
［12］闫蕊.黄花油点草主要有效成分分析研究［D］.汉中:陕西理工大学,2018.
［13］任丽,贾田芊,李兴欢,等.黄花油点草药材的质量标准研究［J］.中国药房,2019,30(8):1083-1090.
［14］Ren L,Wang YZ,Zhang W,et al.Triculata A,a novel compound from Tricyrtis maculata(D.Don）J.F.Macbr.with biological properties［J］.Natural Product Research,2021,35(21):3729-3737.
［15］孙静,任丽,王赟泽,等.阿魏酸甲酯用于制备治疗/预防血栓药物中的应用:中国，111265507A［P］.2020-06-12.
［16］赵宗垒,吴继英.活血化瘀中药治疗心脑血管疾病的药理药效及临床应用评价［J］.名医,2019(9):239.
［17］杭传珍.活血化瘀治则的药理学基础［J］.中医临床研究,2019,11(1):34-35.
［18］孙静,闫咏梅,夏新华,等.一种治疗缺血性脑血管疾病的中药提取物及其制备方法:中国，103356861B［P］.2015-04-01.
［19］孙静,贾田芊.黄花油点草活血作用物质基础的初步研究［J］.中药材,2016,39(2):419-421.
［20］孙静,张小飞,刘妍如,等.一种黄花油点草提取物以及从黄花油点草提取物中分离丁香树脂醇的方法:中国，114652786A［P］.2022-06-24.
［21］Wang YZ,Zhang W,Ren L,et al.Trimacoside A,a high molecular weight antioxidant phenylpropanoid glycoside from Tricyrtis Maculata［J］.Records of Natural Products,2021,15(3):194-201.
［22］闫蕊,赵桦.黄花油点草总黄酮超声提取工艺的响应面优化及抗氧化性分析［J］.食品工业科技,2018,39(10):190-196,203.
［23］中国医师协会中西医结合医师分会,中国中西医结合学会心血管病专业委员会,中国中西医结合学会重症医学专业委员会,等.急性心肌梗死中西医结合诊疗指南［J］.中国中西医结合杂志,2018,38(3):272-284.
［24］陈可冀,张敏州,霍勇.急性心肌梗死中西医结合诊疗专家共识［J］.中国中西医结合杂志,2014,34(4):389-395.
［25］Yu SS,Guo Q,Jia TQ,et al.Mechanism of action of nicotiflorin from Tricyrtis Maculata in the treatment of acute myocardial infarction:from network pharmacology to experimental pharmacology［J］.Drug Design,Development and Therapy,2021,15:2179-2191.
［26］孙静,王赟泽.松脂素在制备抑制血栓形成的药物中的用途:中国，113398113A［P］.2021-09-17.
［27］孙静.陕产黄花油点草活血有效部位及其血清指纹图谱的应用研究［D］.长沙:湖南中医药大学,2012.
［28］孙静,寇文龙,刘文文,等.陕产黄花油点草的生药鉴别［J］.中药材,2012,35(5):717-719.
［29］孙静,何晓娟,刘洁琼.HPLC法测定陕西产黄花油点草中烟花苷的含量［J］.中国药房,2015,26(9):1246-1247.
［30］宋小妹,唐志书,王薇,等.太白“七药”研究进展［J］.亚太传统医药,2009,5(2):120-123.
［31］程虎印,王薇,程江雪.“七药”的资源特征及其研发策略［J］.中草药,2014,45(15):2272-2276.
［32］刘小红.“太白七药”的种属关系调查研究［J］.陕西中医学院学报,2009,32(1):55-58.
［33］张娜.黄花油点草生殖生物学研究［D］.汉中:陕西理工学院,2014.
［34］张娜,杨秋琛,赵桦,等.黄花油点草胚胎发育研究［J］.西北植物学报,2014,34(6):1131-1137.
［35］张娜,赵桦,李永玲.黄花油点草大小孢子发生及雌雄配子体发育［J］.西北植物学报,2013,33(8):1589-1594.
［36］Zhang X,Yang HX，Ye K,et al.Oblongolides from endophytic fungus Phoma bellidis neerg.harbored in Tricyrtis Maculata(D.don）J.F.Macbr［J］.Phytochemistry,2022,198:113126.
［37］Nakayama M,Aihara M,Chen YN,et al.Neuroprotective effects of flavonoids on hypoxia,glutamate,and oxidative stressinduced retinal ganglion cell death［J］.Molecular Vision,2011,17:1784-1793.
［38］曹秦,吴辉,张蓓蓓,等.黄酮类化合物在防治神经退行性疾病中作用的研究进展［J］.中国药理学与毒理学杂志,2015,29(3):457-463.
［39］Huang JL,Fu ST,Jiang YY,et al.Protective effects of Nicotiflorin on reducing memory dysfunction,energy metabolism failure and oxidative stress in multiinfarct dementia model rats［J］.Pharmacology Biochemistry and Behavior,2007,86(4):741-748.
［40］贾田芊,郭天元,田曼,等.LCMS/MS测定烟花苷在大鼠体内及排泄物中分布情况［J］.中药药理与临床,2020,36(6):69-76.
［41］贾田芊,田曼,翟思成,等.LCMS/MS测定大鼠血浆中烟花苷浓度及其药代动力学和生物利用度［J］.中国现代中药,2019,21(12):1625-1629.
Memo
基金项目：国家自然科学基金项目（82174111）；陕西中医药大学学科创新团队项目（2019-YL12）