[1] She Shoujun Zheng Rucheng Cheng Lei Chen Zheng Pang Jian,.Box - Behnken Response Surface Methodology for Optimizing the Ethanol Extraction Process of Glycosides from Cortex Paeoniae Sinensis [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2019, (04): 21-27. [doi: 10.13424/j.cnki.jsctcm.2019.04.007]
Box - Behnken Response Surface Methodology for Optimizing the Ethanol Extraction Process of Glycosides from Cortex Paeoniae Sinensis
- Article number:
- 2096 -1340( 2019) 04 -0021 -07
- ZTFLH:
- R284.2
- Code:
- A
- Abstract:
- Objective To optimize the ethanol extraction process of glycosides from cortex paeoniae sinensis. Methods On the basis of single factor experiment, taking ethanol concentration, solid - liquid ratio and extraction time as independent variables, and taking the comprehensive scores of paeoniflorin oxide, paeoniflorin, benzoyl paeoniflorin and extract yield as dependent variables, response surface methodology based on Box - Behnken design was used to optimize the ethanol extraction process of glycosides from cortex paeoniae sinensis. Results The optimum ethanol extraction process was 60% ethanol, the ratio of material to liquid was 1: 70, extraction twice, 90 minutes each time. Conclusion The optimized ethanol extraction process is simple, stable and feasible, which can provide reference for further production development and application research.
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Memo
基金项目：安徽省教育厅 ２０１８年度高校自然科学研究重点项目（ＫＪ２０１８Ａ０７４７）