[1] Wang Pan, Rong Peirong, Liu Fengli, et al. Effect of Nourishing Kidney - Yin and Warming Kidney - Yang on DCs Function in Patients with HBV Immune Tolerance [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2019, (02): 50-54. [doi: 10.13424/j.cnki.jsctcm.2019.02.017]
Effect of Nourishing Kidney - Yin and Warming Kidney - Yang on DCs Function in Patients with HBV Immune Tolerance
- Article number:
- 2096-1340(2019)02-0050-05
- ZTFLH:
- R521.6+1
- Code:
- A
- Abstract:
- To compare the effects of nourishing kidney - yin method and warming kidney - yang method on DCs function in patients with HBV immune tolerance. Method Peripheral blood was collected from 20 patients with HBV immune tolerance and 10 healthy persons. Mononuclear cells ( PBMCs) were isolated by immunomagnetic bead method. DC cells were isolated, extracted and cultured. Rat plasma containing drugs for nourishing kidney yin and warming kidney Yang was used for culture intervention. CD80, CD86, HLA - DR and IL -12 levels on the surface of DCs were detected. Result The expression rates of CD80, CD86, HLA - DR and IL - 12 in DCs treated with drug plasma were increased, especially in CD80 and IL -12 ( p <0. 05) . The plasma of warming and tonifying kidney - yang drug was better than that of nourishing kidney - yin drug and Guifu decoction, and that of Liuwei Dihuang group was better than that of Guifu group. Conclusion Both the methods of warming and tonifying kidney - yang and nourishing kidney - yin canimprove the function of DC cells from patients with HBV immune tolerance, and the method of warming and tonifying kidney - yang has more significant effect on DCs function of patients with HBV immune tolerance.
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Memo
基金项目：陕西省教育厅资助项目（１１ＪＫ０８６８）