[1] Guan Qian Jiao Junzhe Ye Zihao Wang Keqiong,.Clinical Analysis of Yipi Fuzheng Recipe combined with Chemotherapy in the Treatment of Advanced Esophageal Cancer [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2019, (01): 150-154,158. [doi: 10.13424/j.cnki.jsctcm.2019.01.045]
Clinical Analysis of Yipi Fuzheng Recipe combined with Chemotherapy in the Treatment of Advanced Esophageal Cancer
- Article number:
- 2096-1340(2019)01-0150-06
- ZTFLH:
- R735.1
- Code:
- A
- Abstract:
- To observe the clinical effect of Yipi Fuzheng Decoction combined with chemotherapy in the treatment of advanced esophageal cancer. Method: 41 patients with advanced esophageal cancer were randomly divided into treatment group ( 20 cases) and control group ( 21 cases) . The control group was treated with paclitaxel plus nedaplatin chemotherapy alone, while the treatment group was treated with Yipi Fuzheng Recipe on the basis of the control group. The two groups were observed for 2 cycles, 21 days a cycle. The scores of TCM syndromes, immune function, KPS score, incidence of toxic and side effects after chemotherapy, short - term efficacy evaluation and other indicators were observed before and after treatment in the treatment group and the control group, and the statistical evaluation was made. Result: 1. There were statistical differences between the treatment group and the control group in the aspects of TCM syndrome score, improvement of TCM syndrome efficacy, KPS score and immune index ( P < 0. 05) . 2. In alleviating toxic and side effects, there were significant differences between the treatment group and the control group in improving nausea and vomiting symptoms before and after treatment ( P < 0. 05) . 3. In terms of short - term efficacy, the effective rate of tumor remission in the treatment group was higher than that in the control group, but there was no statistical difference between the two groups. ( P > 0. 05) . Conclusion: Yipi Fuzheng Decoction combined with chemotherapy in the treatment of advanced esophageal cancer can effectively alleviate the clinical symptoms of patients, improve the KPSscore and quality of life of patients, effectively reduce the incidence of side effects such as nausea and vomiting, and improve the immune function of patients. It provides an optimized scheme for the treatment of esophageal cancer with integrated traditional Chinese and Western medicine.
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Memo
基金项目：陕西省中医药管理局资助项目（ＬＣＰＴ０２０